Wegener's Granulomatosis

In Wegener's granulomatosis is a form of vasculitis which affects the lungs kidneys and other organs. Asides stinged blood vessels, Wegener's granulomatosis produces a type of inflammatory tissue known as granuloma. Though vasculitis can belemish any organ system, Wegener's granulomatosis mainly strikes the respiratory tract (sinuses, nose, trachea [windpipe] and lungs) and the kidneys.

This disorder can focus people at any age and affect men and women equally. It is sporadic in African Americans in comparison  with Caucasians. Marks and symptoms of Wegener's granulomatosis may develop abruptly or eventually. Early diagnosis and treatment may lead to a full repossession. Without treatment, this disease can be fatal.

Wegener's Granulomatosis (WG) is an uncommon disease which strikes about 1 in 20,000 to 1 in 30,000 people. Wegener's granulomatosis is an unusual disease, in which the blood vessels are inflamed (vasculitis). There is no certain cause of WG; but it is not infectious, and there is no proof that it is hereditary. It paradigmatically involves inflammation of the arteries which supply blood to the tissues of the lungs, the nasal passages (sinuses), and the kidneys.

Another organ systems which can be influneced by the disease involve the nervous system, ears, eyes, heart, and skin. It most generally occurs in the 4th and 5th decade of life. Patients are divided equally between males and females. It appears which Caucasians are far more commonly striked than other racial groups.

Causes of Wegener Granulomatosis

The common Causes of Wegener Granulomatosis :

• The cause of Wegener granulomatosis is unknown
• The etiology of WG remains unknown, though evolving evidence supports an autoimmune cause.

Symptoms of Wegener Granulomatosis

Some Symptoms of Wegener Granulomatosis :

• Cough
• Appetite loss
• Fever
• Shortness of breath (dyspnea)
• Joint aches and swelling
• Double or decreased vision
• Eye redness, burning or pain

Treatment of Wegener Granulomatosis

• Glucocorticoids
• Antibiotics
• Methotrexate
• Cyclophoshamide
• Ciclosporin Intravenous immunoglobulin
• Newer biologic agents
• Potassium iodide solution.

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